Proliferating Cell Nuclear Antigen in the Era of Oncolytic Virotherapy
Proliferating cell nuclear antigen (PCNA) is a well-documented accessory protein of DNA repair and replication.It belongs to the sliding clamp family of proteins that encircle DNA and acts as a mobile docking platform for interacting proteins to mount and perform their metabolic tasks.PCNA presence is ubiquitous to all cells, and when located in th